Comparison of sodA and 16S rDNA sequencing for accurate species-level identification of viridans group streptococci (VGS) isolated from patients with infective endocarditis
نویسندگان
چکیده
Background Viridans group streptococci (VGS) are commensal flora of the upper respiratory tract in humans and can cause serious infections, like infective endocarditis, septicemia, and meningitis. Accurate identification of VGS to the species level is difficult because they share many physiological characteristics. We report a study using sequencing of 16S ribosomal DNA (rDNA) gene and sodA gene to discriminate VGS up to species level.
منابع مشابه
GyrB polymorphisms accurately assign invasive viridans group streptococcal species.
Viridans group streptococci (VGS) are a heterogeneous group of medically important bacteria that cannot be accurately assigned to a particular species using conventional phenotypic methods. Although multilocus sequence analysis (MLSA) is considered the gold standard for VGS species-level identification, MLSA is not yet feasible in the clinical setting. Conversely, molecular methods, such as sod...
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